Microneedling with Rejuran
In Riverside and Orange County

At MedSkinEssentials, Rejuran microneedling has become a favorite for patients who want authentic, regenerative results without a “done” look. It’s gentle enough for sensitive and reactive skin, yet effective enough to visibly improve fine lines, dehydration, and early textural changes over a series of sessions.

Your Rejuran Microneedling Treatment

Your treatment begins with a thorough cleanse and, if needed, a topical numbing cream to keep you comfortable. Your provider then applies Rejuran directly to the skin and uses a fine-needle microneedling device to create controlled micro-channels, allowing the polynucleotide serum to reach the dermis where it can stimulate collagen and elastin production. Most sessions take about 30 to 45 minutes from start to finish. Afterward, you may notice mild redness or small bumps at the injection sites, similar to mosquito bites, which typically settle within a day or two. Because downtime is minimal, most patients return to normal activities the same day, and visible improvements in hydration and glow tend to build over the following weeks as new collagen forms.

Common Areas Treated With Rejuran Microneedling

Rejuran microneedling is most often used on areas where skin is thinner, more delicate, or shows early signs of aging and stress. Common treatment areas include:

• Full face, for overall tone, texture, and hydration
• Under-eye area, to soften fine lines and improve crepiness
• Neck and décolletage, where collagen loss shows early
• Acne-prone or scarred skin, to support smoother texture
• Dull, dehydrated, or reactive skin that needs a barrier reset

Because Rejuran works with the skin’s healing response rather than against it, it’s a versatile option for concerns that other treatments can’t always reach comfortably.

Who Can Benefit From Rejuran Microneedling?

Rejuran microneedling is a great fit for men and women who want visible improvement in skin quality without the more dramatic changes associated with fillers or neuromodulators. It’s especially well suited to patients with sensitive, reactive, or easily irritated skin, since Rejuran is known for calming inflammation rather than triggering it. Patients managing early fine lines, dehydration, mild acne scarring, or a dull complexion often see meaningful improvement over a series of treatments. As with any microneedling-based procedure, patients with active acne breakouts, certain skin infections, or bleeding disorders may need to explore other options first. During your consultation, our providers will review your skin goals and medical history to confirm you’re a good candidate.

Combining Rejuran Microneedling With Other Treatments

Because Rejuran focuses on regeneration rather than volume or muscle relaxation, it pairs naturally with many of our other treatments. Patients often combine it with RF microneedling for added skin tightening, or with PRF microneedling to layer two regenerative therapies for even more collagen support. For patients also interested in restoring lost facial volume, Sculptra is a popular complement, while a chemical peel or dermaplane facial beforehand can help Rejuran absorb more evenly. Your provider will help you build a treatment plan and schedule that fits your skin goals, whether that means starting with Rejuran alone or layering it into a broader rejuvenation package.

Why Choose MedSkinEssentials for Rejuran Microneedling?

Our providers are trained specifically in polynucleotide therapies and understand how to layer Rejuran with microneedling depth, spacing, and technique for each patient’s skin type and goals. We start every new patient with a consultation, and you can even get a head start with our online skin quiz to help us understand your concerns before you arrive. With convenient locations in Riverside and Tustin, CA, and a results gallery of real patient outcomes, MedSkinEssentials has built a reputation on natural-looking, authentic results, not one-size-fits-all treatment.